Protein Details: Putative cyclic nucleotide-gated ion channel 8

Protein ID

ICDB_Pro_1497

Protein Name

Putative cyclic nucleotide-gated ion channel 8

Gene Name

CNGC8 At1g19780 F14P1.12 F6F9.17

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

753 amino acids

AlphaFoldDB

AF-Q9FXH6-F1-model_v4.pdb

Function

Putative cyclic nucleotide-gated ion channel.

Sequence

MYKSQYISGHREKFVRLDDTDSRVSMSSNATGMKKRSCFGLFNVTSRGGGKTKNTSKSFREGVKIGSEGLKTIGKSFTSGVTRAVFPEDLRVSEKKIFDPQDKTLLLWNRMFVISCILAVSVDPLFFYLPIVDNSKNCIGIDSKLAVTTTTLRTIIDVFYLTRMALQFRTAYIAPSSRVFGRGELVIDPAKIAERYLTRYFIVDFLAVLPLPQIAVWKFLHGSKGTDVLPTKQALLHIVITQYIPRFVRFIPLTSELKKTAGAFAEGAWAGAAYYLLWYMLASHITGAFWYMLSVERNDTCLRSACKVQPDPKVCVQILYCGSKLMSSRETDWIKSVPDLFKNNCSAKSDESKFNYGIYSQAVSSGIVSSTTFFSKFCYCLWWGLQNLSTLGQGLQTSTYPGEVLFSIAIAVAGLLLFALLIGNMQTYLQSLTVRLEEMRIKRRDSEQWMHHRSLPQNLRERVRRYDQYKWLETRGVDEENIVQSLPKDLRRDIKRHLCLNLVRRVPLFANMDERLLDAICERLKPSLYTESTYIVREGDPVNEMLFIIRGRLESVTTDGGRSGFFNRGLLKEGDFCGEELLTWALDPKAGSNLPSSTRTVKALTEVEAFALEAEELKFVASQFRRLHSRQVQQTFRFYSQQWRTWAACFIQAAWRRHLRRKIAELRRKEEEEEEMDYEDDEYYDDNMGGMVTRSDSSVGSSSTLRSTVFASRFAANALKGHKLRVTESSKSLMNLTKPSEPDFEALDTDDLN

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

BINDING 508..638; /ligand="a nucleoside 3,5-cyclic phosphate"; BINDING 579; /ligand="a nucleoside 3,5-cyclic phosphate"

Disease

Location

DOI ID

10.1038/35048500; 10.1111/tpj.13415; 10.1104/pp.126.4.1646

RefSeq

NP_173408.2